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Respiratory symptoms were defined by affirmative answers to the following questions 20 : Longstanding cough Have you had a longstanding cough during the last year?

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45 The findings that dual users of cigarettes and e-cigarettes have worse HRQoL than 5-year cessation may reflect the fact that these persons tend to be heavier, more dependent smokers 46 compared to 5-year cessation, many of whom may not have been heavy cigarette smokers to begin with

The first album of original material by the Rolling Stones since 2005's A Bigger Bang, Hackney Diamonds reached No.1 in 20 countries and features guest contributions from Elton John, Lady Gaga, Paul McCartney, Stevie Wonder, and former Rolling Stones bassist Bill Wyman